Dosimetric Influence of Uterus Position in Cervix Cancer High-dose-rate Brachytherapy
نویسندگان
چکیده
Brachytherapy is an integrating component for the treatment of locally advanced cervical cancer. While most women present anteverted or intermediary position uterus, only 20–25% have retroverted uterus. We evaluated 418 high-dose-rate brachytherapy plans of patients diagnosed with biopsy proven cervical cancer. Urinary bladder and rectal points were identified on the orthogonal digital X-ray images according to ICRU Report no.38. The brachytherapy plans were divided according to uterus position into three groups, anteverted, intermediary and retroverted, respectively. The statistical analysis of the dosimetric data confirmed that uterus axis influences radiation doses received by the urinary bladder and rectum.
منابع مشابه
Study of dosimetric and spatial variations due to applicator positioning during inter-fraction high-dose rate brachytherapy in the treatment of carcinoma of the cervix: A three dimensional dosimetric analysis
Background: This study evaluates dosimetric and spatial variations in inter–fraction applicator positioning in high dose rate (HDR) brachytherapy. Materials and Methods: This study includes 25 retrospective patients of carcinoma of the cervix. Each patient received 5 fractions of HDR intracavitary brachytherapy. High Risk-Clinical Target Volume (HR-CTV) were drawn on CT images. First impl...
متن کاملRadiation sigmoiditis mimicking sigmoid colon cancer after radiation therapy for cervical cancer: the implications of three-dimensional image-based brachytherapy planning
External-beam radiation therapy with intracavitary high-dose-rate brachytherapy is the standard treatment modality for advanced cervical cancer; however, late gastrointestinal complications are a major concern after radiotherapy. While radiation proctitis is a well-known side effect and radiation oncologists make an effort to reduce it, the sigmoid colon is often neglected as an organ at risk. ...
متن کاملDosimetric feasibility of stereotactic body radiation therapy as an alternative to brachytherapy for definitive treatment of medically inoperable early stage endometrial cancer
PURPOSE This study was designed to evaluate the dosimetric feasibility of definitive stereotactic body radiation therapy (SBRT) for the treatment of medically inoperable early stage endometrial cancer. METHODS CT simulation scans from 10 medically inoperable early stage endometrial cancer patients previously treated with high dose-rate (HDR) intracavitary brachytherapy were used to generate H...
متن کاملDosimetric evaluation of a combination of brachytherapy applicators for uterine cervix cancer with involvement of the distal vagina* Avaliação dosimétrica de uma combinação de aplicadores para braquiterapia de tumores do colo uterino com acometimento da porção distal da vagina
OBJECTIVE: To evaluate an alternative brachytherapy technique for uterine cervix cancer involving the distal vagina, without increasing the risk of toxicity. MATERIALS AND METHODS: Theoretical study comparing three different high-dose rate intracavitary brachytherapy applicators: intrauterine tandem and vaginal cylinder (TC); tandem/ring applicator combined with vaginal cylinder (TR+C); and a v...
متن کاملDosimetric characterization of a high dose rate 192I source for brachytherapy application using Monte Carlo simulation and benchmarking with thermoluminescent dosimetry
Background: The purpose of this project was to derive the brachytherapy dosimetric functions described by American Association of Physicists in Medicine (AAPM) TG-43 U1 based on high dose rate 192I sources. Materials and Methods: The method utilized included both simulation of the designed Polymethyl methacrylate (PMMA) phantom using the Monte Carlo of MCNP4C and benchmarking of the simulation ...
متن کامل